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Research Associate Biology, High Throughput Screening

Amsterdam · Full-time · onsite · Posted 14 Jun 2026

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01

What you will do

About this role

# Research Associate - Bioengineering

Join Cradle's Bioengineering team to develop and run high-throughput workflows for building DNA libraries, expressing and purifying proteins, and running characterization studies. You'll work in a diverse team executing novel wet lab methods for DNA construction and protein optimization pipelines, collaborating with machine learning algorithms.

## Responsibilities

  • Run workflows for DNA synthesis and assembly, protein expression, protein purification, and protein characterisation
  • Effectively document and communicate results, successes, and challenges in a cross-functional environment

## Requirements

  • BSc or equivalent experience in molecular biology, biochemistry, enzymology, metabolic engineering, biophysics, or related fields
  • Demonstrated experience with standard molecular biology techniques such as cloning, in vitro and/or in vivo protein expression systems (e.g. E. coli, B. subtilis, P. pastoris, CHO or HEK cell lines, cell extracts)
  • Motivated to work in a 100% laboratory based role
  • Excitement to learn, contribute, and drive innovation in an early stage startup environment
  • Strong verbal and written communication skills in English
  • Ability to run multiple projects simultaneously while ensuring proper documentation and data organization

## Nice-to-haves

  • Protein purification techniques (e.g. affinity tag purification)
  • Assay development for enzymatic activity or antibody binding assays
  • Protein expression in cell-free systems (cell extracts, myTXTL, PURE)
  • Next-generation sequencing techniques (Illumina, Nanopore, PacBio)
  • Classical high-throughput laboratory automation (robotic liquid handlers, plate readers)
  • High-throughput advanced cloning technologies (site-directed mutagenesis, Gibson Assembly, Golden-Gate Cloning)

Skills & experience

JuniorMolecular biologyDNA synthesis and assemblyProtein expressionProtein purificationProtein characterisationCloningE. coliB. subtilisP. pastorisCHO cell linesHEK cell linesCell extractsAffinity tag purificationEnzyme assaysAntibody binding assaysCell-free protein expressionNext-generation sequencingIlluminaNanoporePacBio
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Where you will work

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Address
Amsterdam · Noord-Holland1107 TKNo exact address
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